For comparison, you can look at the opening to the first Fallout game, but once that homage is over, there’s plenty of new things to gander at:
Just a few details I noticed: There’s a poster for GNN which I assume stands for “Galaxy News Network,” so I’d expect Three Dog to make a return appearance. The Nuka-Cola machines have been re-designed. Some vaults had elevators designed like the main doors. A business is shown as being named “Diamond City Surplus,” which could mean part of the game is set near Diamond City, North Carolina.
I’m sure sharper eyes than mine can place that domed building and the statue of the man on horseback, and I’m hoping the flying pirate ship is based on an actual one that’s a tourist attraction or something. I mean, wastelanders just building pirate ships on their own starts to make me wonder if Borderlands 2 was popular right before the bombs fell.